The immunobiology of pregnancy, and impacts in women with Multiple Sclerosis (MS) or Neuromyelitis Optica Spectrum Disorder (NMOSD)

Subject area of study: 
Multiple sclerosis, pregnancy outcomes
Title of study: 
The immunobiology of pregnancy, and impacts in women with Multiple Sclerosis (MS) or Neuromyelitis Optica Spectrum Disorder (NMOSD)
Brief outline of the study: 

Pregnancy may have beneficial health effects for women with relapsing-remitting MS in the form of less long-term disability. We are seeking to identify the biological mechanisms that underpin this benefit by following Australian women with and without MS over a 3-5 year period. In these women, we will track changes that occur to the immune system before, during, and after pregnancy, and compare these changes against the immune activity in women of the same age who do not have children. The results of this research may help reveal the biological process behind the start and progression of MS and in the development of new treatments. It may also help us to better understand the biological processes behind fertility, miscarriage, and pregnancy-associated conditions such as pre-eclampsia.

Department: 
Neuroscience
Recruitment start date: 
Mon, 15/08/2022
Recruitment end date: 
Wed, 31/12/2025
Contact person title: 
Dr
Contact person first name: 
Vilija
Contact person last name: 
Jokubaitis
Contact email: 
vilija.jokubaitis@monash.edu
Contact phone number: 
(03) 9903 0880
Ethics Committee Project Number: 
Alfred HREC 179/21
Do you have advertising approval?: 
Yes
Approved by: 
Alfred