The vagus nerve in epilepsy
The Baker Heart and Diabetes Institute is conducting a research study to compare how epilepsy affects the control of blood pressure. We are interested in understanding how Vagal Nerve Stimulation (VNS), an effective treatment for drug-resistant epilepsy, works to reduce seizures and to reduce the elevated cardiovascular risk associated with epilepsy.
This study involves inserting a fine needle (microelectrode) either into (i) the vagus nerve in the neck or (ii) the peroneal nerve at the side of the knee. These procedures are not considered painful and are well-tolerated. You will be invited to participate in session (i) and session (ii) on separate days.
To be eligible, you must be:
aged 18–40 years
currently receiving treatment for epilepsy with an implanted VNS device
or a healthy participant without epilepsy